Biestrogen / Progesterone

$ 299.00 USD
(4.5 stars) • 11 reviews

This compounded bioidentical hormone cream combines Biestrogen (50:50 estradiol/estriol) with Progesterone 4%, available at Modern Wellness Clinic in Summerlin, Las Vegas as part of a physician-supervised bioidentical hormone replacement program for women. Rx required.

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Treatment Timeline

Response to bioidentical HRT varies by individual, hormone levels, and application consistency. Many patients notice changes in sleep, mood, and energy within 4-8 weeks. Hormone levels are monitored through follow-up labs to guide dose adjustments.

Suggested Usage

Per Provider Protocol

Provider Note

Bioidentical hormone creams are compounded to individual patient needs based on labs and symptom profile. All patients receive baseline and follow-up hormone panels to ensure therapeutic levels remain within a safe and appropriate range. — Modern Wellness Clinic Clinical Team.

Answers from the clinical team at Modern Wellness Clinic in Summerlin, Las Vegas.

What is Biestrogen and how is it different from standard HRT?

Biestrogen is a compounded estrogen containing both estradiol and estriol in a 50:50 ratio. Unlike standard HRT which typically uses synthetic or single-estrogen formulations, bioidentical hormones are molecularly identical to those your body produces, which some patients and providers prefer for personalized hormone support.

Do I need a prescription for this compounded cream?

Yes. This is a compounded prescription medication. A provider evaluation at Modern Wellness Clinic is required before it can be dispensed. The formula is prepared based on your clinical assessment and lab results.

Does Modern Wellness Clinic accept insurance for women's hormone therapy in Las Vegas?

We accept BCBS (excluding Pathway HMO), Aetna, United Healthcare, Humana, and Optum. Coverage for hormone therapy varies by plan and diagnosis. Contact us at (702) 463-9159 for a free benefits check before your first visit.

Do I need labs before starting Biestrogen + Progesterone therapy at Modern Wellness Clinic?

Yes. Baseline hormone labs including estradiol, progesterone, FSH, and a comprehensive metabolic panel are required. Labs can be ordered as part of your initial consultation at our Summerlin clinic or via telehealth.

Is bioidentical HRT available via telehealth in Nevada?

Yes. Modern Wellness Clinic offers telehealth consultations for women's hormone health statewide in Nevada. Compounded medications can be shipped to your home through our partner pharmacies following a successful provider evaluation.

How often are hormone levels monitored on bioidentical HRT at Modern Wellness Clinic?

Follow-up hormone panels are typically reviewed 6-8 weeks after initiating therapy and then every 3-6 months for ongoing monitoring. Dose adjustments are made based on lab results and how you feel clinically.

Bioidentical Hormone Therapy for Women at Modern Wellness Clinic in Las Vegas

This compounded bioidentical hormone cream combines two forms of estrogen — estradiol and estriol in a 50:50 ratio (Biestrogen) — with progesterone 4%, in a transdermal cream applied to the skin. At Modern Wellness Clinic in Summerlin, Las Vegas, bioidentical hormone therapy for women is provided as part of a physician-supervised program that begins with comprehensive baseline hormone labs and clinical evaluation, and is maintained through regular follow-up panels and provider monitoring.

Why Biestrogen? The Rationale for a Two-Estrogen Approach

Estradiol (E2) is the primary and most potent estrogen in premenopausal women, responsible for maintaining bone density, cardiovascular tone, vaginal tissue health, skin elasticity, cognitive function, and mood stability. Its decline during perimenopause and menopause is the primary driver of the most common symptoms our patients describe: hot flashes, night sweats, sleep disruption, vaginal dryness, mood instability, and mental fog. Estriol (E3) is a weaker estrogen that is particularly relevant to vaginal and urinary tract tissue health. The 50:50 ratio in this formula provides estradiol’s systemic effects alongside estriol’s local tissue support. The progesterone component is included to balance estrogen’s proliferative effects on the uterine lining — progesterone is a standard component of any complete HRT protocol for women with an intact uterus and is also used for its sleep-supporting and mood-stabilizing properties.

Why Bioidentical Hormones at Modern Wellness Clinic?

Bioidentical hormones are molecularly identical to the hormones produced by the human body, in contrast to some synthetic hormone analogs used in conventional HRT. Our bioidentical hormone replacement program at Modern Wellness Clinic in Las Vegas uses compounded preparations that allow individual dose customization based on your specific lab values and symptom profile — rather than a fixed commercial dose. This approach requires more frequent monitoring and a more engaged provider relationship, which is exactly what Modern Wellness Clinic is designed to deliver.

Bioidentical Hormone Therapy for Women at Modern Wellness Clinic in Las Vegas

This compounded bioidentical hormone cream combines two forms of estrogen — estradiol and estriol in a 50:50 ratio (Biestrogen) — with progesterone 4%, in a transdermal cream applied to the skin. At Modern Wellness Clinic in Summerlin, Las Vegas, bioidentical hormone therapy for women is provided as part of a physician-supervised program that begins with comprehensive baseline hormone labs and clinical evaluation, and is maintained through regular follow-up panels and provider monitoring.

Why Biestrogen? The Rationale for a Two-Estrogen Approach

Estradiol (E2) is the primary and most potent estrogen in premenopausal women, responsible for maintaining bone density, cardiovascular tone, vaginal tissue health, skin elasticity, cognitive function, and mood stability. Its decline during perimenopause and menopause is the primary driver of the most common symptoms our patients describe: hot flashes, night sweats, sleep disruption, vaginal dryness, mood instability, and mental fog. Estriol (E3) is a weaker estrogen that is particularly relevant to vaginal and urinary tract tissue health. The 50:50 ratio in this formula provides estradiol’s systemic effects alongside estriol’s local tissue support. The progesterone component is included to balance estrogen’s proliferative effects on the uterine lining — progesterone is a standard component of any complete HRT protocol for women with an intact uterus and is also used for its sleep-supporting and mood-stabilizing properties.

Why Bioidentical Hormones at Modern Wellness Clinic?

Bioidentical hormones are molecularly identical to the hormones produced by the human body, in contrast to some synthetic hormone analogs used in conventional HRT. Our bioidentical hormone replacement program at Modern Wellness Clinic in Las Vegas uses compounded preparations that allow individual dose customization based on your specific lab values and symptom profile — rather than a fixed commercial dose. This approach requires more frequent monitoring and a more engaged provider relationship, which is exactly what Modern Wellness Clinic is designed to deliver.

Side Effects and Monitoring for Biestrogen + Progesterone Therapy

Bioidentical hormone creams are generally well tolerated when initiated at appropriate doses based on lab values and titrated conservatively. At Modern Wellness Clinic in Las Vegas, all patients receive baseline labs before starting and follow-up panels at 6-8 weeks to evaluate hormone levels and guide any dose adjustments. The goal is optimal symptom relief at the lowest effective dose.

Early Adjustment Period Effects

During the first 4-8 weeks as hormone levels change, some patients experience breast tenderness or fullness, mild bloating, headache, mood fluctuations, or temporary changes in sleep as the body adjusts. These are often signs that the dose is being absorbed and taking effect — they are assessed at the first follow-up labs and managed through dose titration if needed.

Application Site Effects

Transdermal creams can cause mild skin irritation, redness, or itching at the application site in a small subset of patients. Rotating the application site and ensuring the cream is fully absorbed before covering the area typically minimizes these effects.

Estrogen-Specific Considerations

Estrogen therapy carries the same category-level considerations as any form of HRT: it is not appropriate for women with a personal history of certain estrogen-sensitive cancers, active thromboembolic disease, or undiagnosed abnormal vaginal bleeding. Your provider at Modern Wellness Clinic will review your full medical history and these contraindications before prescribing. Regular follow-up and monitoring are a required part of this program.

Clinical Notes

This is a compounded prescription medication. A provider evaluation and baseline labs are required before initiation. Purchasing initiates the clinical evaluation process at Modern Wellness Clinic. All contraindications, monitoring requirements, and ongoing lab schedules are reviewed with your provider at your consultation and follow-up visits.