Semaglutide vs Tirzepatide: Which Is Better for Weight Loss?

Trying to choose between semaglutide and tirzepatide for weight loss?

July 30, 2025

Semaglutide vs Tirzepatide: Which Is Better for Weight Loss?

If you’re exploring medical weight loss options in Las Vegas, you’ve likely heard about two powerful medications: semaglutide and tirzepatide. While both can deliver impressive results, they work a little differently—and one may be a better fit for your body and goals.

At Modern Wellness Clinic in Summerlin, we offer both options with full medical support. Here’s what you need to know before choosing.

What Are They?

  • Semaglutide (found in medications like Ozempic and Wegovy) is a GLP-1 receptor agonist. It mimics a hormone that helps regulate appetite and blood sugar.
  • Tirzepatide (found in Mounjaro) is a dual GIP and GLP-1 receptor agonist. This means it works on two hormone pathways, which may lead to even greater appetite control and weight loss.

Key Differences

CategorySemaglutideTirzepatideHormones TargetedGLP-1GLP-1 + GIPAverage Weight Loss12–15% of body weightUp to 20% in some casesDosingWeekly injectionsWeekly injectionsFDA Approved ForType 2 Diabetes (Ozempic), Weight Loss (Wegovy)Type 2 Diabetes (Mounjaro) — Weight loss approval expected soonCostOften covered by insuranceNewer, sometimes less covered

While tirzepatide is showing slightly higher weight loss in clinical studies, semaglutide is still extremely effective and better known at this time.

Which One Is Right for You?

Both options help you feel fuller faster and reduce cravings—but your best choice depends on:

  • Your current health
  • Whether you’ve tried one before
  • How your body responds to treatment
  • Your budget and insurance coverage

At Modern Wellness Clinic, we review your full health picture and help you decide what fits best.

Side Effects Comparison

Both medications may cause temporary nausea, stomach upset, or fatigue at first. These effects often go away as your body adjusts.

Some patients find one easier to tolerate than the other. Our medical team works closely with you to monitor side effects and adjust the dose as needed.

Why Las Vegas Patients Choose Us

We’re more than just a weight loss provider. At Modern Wellness Clinic in Summerlin, we:

  • Offer both semaglutide and tirzepatide
  • Do full lab work to understand your baseline
  • Build a complete plan with nutrition and follow-ups
  • Monitor your results and make changes to keep you on track

Weight loss should feel supported, not confusing—and we’re here to make that happen.

Ready to Start Your Journey?

Choosing between semaglutide and tirzepatide doesn’t have to be stressful. With the right team behind you, weight loss can finally feel achievable.

Schedule your consultation today at Modern Wellness Clinic in Las Vegas and let’s figure out the right path for you.

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