Rapamycin (Sirolimus)

Advanced Longevity and Cellular Health Support:
Rapamycin, also known as Sirolimus, is a groundbreaking compound studied for its potential to slow biological aging and extend lifespan. It works by modulating the mTOR pathway — a key regulator of cellular growth, metabolism, and repair — helping the body maintain healthier cellular function over time.

Promotes Healthy Aging and Vitality:
Research suggests that controlled, intermittent Rapamycin use may help improve metabolic health, reduce inflammation, and enhance resilience to age-related decline. It supports optimal cellular performance, contributing to improved energy, recovery, and overall longevity.

Immune and Inflammatory Regulation:
Originally developed as an immunomodulator, Rapamycin helps balance immune system activity. This regulation can support the body’s natural defenses while reducing chronic inflammation associated with aging and metabolic dysfunction.

Possible Side Effects of Rapamycin (Sirolimus)

Rapamycin (also known as Sirolimus) is a powerful mTOR inhibitor and immunomodulatory therapy. It must be used under tight medical supervision due to a wide range of potential side effects. Below is a breakdown of what patients should be aware of.

Common / Mild Side Effects

• Mouth ulcers, sores, or irritation
• Gastrointestinal discomfort: nausea, diarrhea, abdominal pain, constipation
• Headache, dizziness
• Muscle aches, joint pain
• Swelling (edema) in feet, ankles, hands
• Flushing or warmth in the face or skin
• Skin rash, acne, or mild irritation
• Elevated blood lipids: cholesterol and triglycerides
• Elevated blood pressure
• Cold/flu-like symptoms, increased risk of mild infections

Less Common / Intermediate Side Effects

• Impaired wound healing or slow recovery of surgical/incisional wounds
• Increased protein in the urine (proteinuria)
• Changes in kidney function
• Low blood counts (e.g. anemia, low platelets, low white cells)
• Mouth sores or stomatitis
• Fluid imbalance
• Respiratory symptoms (e.g. cough)
• Changes in skin pigmentation or texture

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